The pancreas is the most important part of the digestive system with exocrine and endocrine function. Responsible for the metabolism and activity of the enzymatic apparatus.
Its hormones supply the necessary biological substances to the tissue, provide balanced processes of the vital activity of the body.
The primary symptoms of endocrine pathology appear in functional disorders of the pancreas. The growth of blood glucose on the background of reduced insulin production or stopping its production leads to pancreatic diabetes.
All metabolic processes are disturbed, acid-base balance is abnormal. In order to prevent life-threatening pathology, it is necessary to know how great is the connection between the pancreas and diabetes.
What pancreatic hormone increases blood sugar?
Before detecting insulin, various groups of pancreatic cells were detected. The hormone glucagon was discovered in the 20s. But only 40 years later, it was determined that it performs the most important physiological function - it exchanges acetone bodies and glucose.
Glucagon is an insulin antagonist. Formed by alpha cells. Together with insulin, it adjusts blood glucose levels. Hormones are directly related to each other. Insulin provides glucose stability, supports the necessary level of amino acids. Glucagon has stimulating properties. It binds the necessary substances, sends them into the blood.
What does the pancreas look like
Glucagon is directly related to the formation of glucose, the normalization of its optimal content. The effect of the hormone on the production of monosaccharide is determined by its functions.
Glucagon stimulates specific receptors that activate amino acid synthesis. Thus, the concentration of glucose increases, and the cells of the body receive all the necessary biologically active substances.
An additional function of glucagon is to stimulate the breakdown of connective tissue lipids. This significantly reduces blood cholesterol levels. Excess hormone contributes to the formation of malignant tumors.
Such a pancreatic hormone, as glucagon is actively produced in the following cases:
- low free glucose concentration;
- physical exercise;
- lack of food;
- severe stress;
- high content of adrenaline and norepinephrine.
How is the work of the pancreas associated with the development of diabetes?With a lack or low bioavailability of insulin, the pancreas undergoes significant changes.
Deformation of the islets of Langerhans is noted. Due to dystrophic lesions, the size of endocrine cells is reduced. Some of them die.
Subsequent pathological changes develop in two scenarios. The first option leads to pancreatitis. The second causes the death of the body. Consequently, diabetes not only alters the work of the pancreas, but also is able to destroy it.
Since the body produces biologically active substances that control metabolic processes, its functional changes in the form of reducing or stopping insulin production are classified as diabetes. Failure of the exchange of carbohydrates of the first type is considered dangerous.
The patient uses daily insulin injections.
Without a sufficient amount of a hormone, the process of glucose conversion becomes impossible, the increased blood sugar is excreted through the urine.
According to statistics, up to 70% of patients suffering from hyperglycemia, are faced with the development of chronic inflammation of the digestive organ.
The mechanism of development of pancreatic diabetes
A third of patients with sluggish inflammation of the pancreas acquires pancreatic diabetes.
The disease occurs as a result of chronic pathology, characterized by a long course with irreversible changes in the cells.
In a severe process, a large percentage of the healthy part of the gland is replaced by connective tissue. Gradually formed exocrine insufficiency, expressed by a small number of digestive enzymes.
In parallel, intrasecretory dysfunction develops. It forms cell immunity to glucose, then triggers diabetes. But the mechanism of the formation of pathology is not considered natural. Patients with persistent inflammation of the pancreas still have the opportunity to avoid severe complications.
Synchronous development of pancreatitis with impaired glucose uptake is the close location of the exocrine organ to the islets of Langerhans. The cellular structures of the endocrine segment synthesize hormonal substances. The exocrine organ produces digestive juices.
Islets of Langerhans
Close proximity leads to the spread of lesion processes in one part of an organ to nearby cells of another type. Local pathological changes affect the digestive cells. Pancreatitis develops. It becomes a pretext for the formation of diabetes.
The parallel course of hyperglycemia and chronic inflammation of the gland makes treatment more difficult. The elimination of pancreatic inferiority and the restoration of carbohydrate metabolism require the simultaneous administration of hormonal and enzyme drugs.
The internal picture of the disease is formed as follows:
- acute pancreatitis is combined with periods of remission;
- symptoms of impaired digestion appear;
- glucose immunity is formed;
- hyperglycemia develops.
Diabetes after removal of the pancreas
Today's advances in medicine are great, but the removal of an organ is considered a difficult intervention, so the physical existence after it changes dramatically.
A serious complication of surgery - type 1 diabetes. Pathology develops on the background of stopping the production of insulin.
Complete removal of the gland leads to a persistent rise in glucose. An injection of a hormone is required. Enzyme deficiency causes impaired digestive processes. The occurrence of hyperglycemia requires lifelong insulin therapy.
The patient is learning how to take medicines, self-inject drugs with the help of injections. Simple procedures are easily mastered. Medicine supports people undergoing surgery. Medical recommendations help to adapt to the new life.
Drugs for diabetes
An unfavorable scenario of diabetes is the development of fatty hepatosis, in which liver cells accumulate a large number of lipids.
Specific changes in metabolism provoke such a pathology: a decrease in stocks of the polysaccharide, an increased amount of fatty blood acids. Progressive chronic process contributes to the growth of intercellular tissues, causes serious organ damage.
Tablets Carsil and Carsil forte
Since fatty degeneration in diabetes is the result of a persistent increase in blood sugar, the elimination of abnormalities in the liver cells implies, above all, therapy for the underlying disease. Normal glucose uptake indicators are a paramount issue for a patient with impaired metabolism.
Hepatoprotectors improve liver function. Therapeutic treatment regimen includes Kars. As part of the drug is not dextrose, which increases blood sugar levels. Diabetes requires an increased daily dosage of the hepatoprotector.
The course is chosen individually. An acute form or severe intoxication of the body requires a monthly intake.
Essentiale forteA frequent companion of developing diabetes is a change in the metabolism of hepatocytes. This complication is characterized by the transformation of tissues of the organ of non-inflammatory genesis.
Lack of treatment provokes the development of hepatitis, and further progression of the pathology threatens with cirrhosis.
Negative processes cause impaired blood circulation, which further complicates the condition of the gland, leading to the development of deficiency.
The development of pathological conditions affecting the functioning of the cells of an organ provokes a breakdown of the bonds between complex lipids and biological catalysts on the surface of cells, their organelles. This causes a failure of enzymatic activity, a decrease in regenerative capacity. Reducing drugs help prevent exacerbation.
The group of hepatoprotectors, renewing the functionality of liver cells is Essentiale Forte. Its use is considered an excellent way to cure the pancreas, prevent the development of complications.
Essentiale and Essentiale Forte
The use of Essentiale Forte, even with serious pathological changes, stops the degradation of the liver tissue, restores the performance of the organ. Phospholipids, which contain the drug, due to the presence of essential fatty acids fall into the ruined areas of the membranes. Embedding helps to restore the integrity of structures, strengthen regeneration processes, increase the cell wall porosity.
How to restore the correct work of the pancreas:
Summing up, we can say that diabetes not only significantly reduces the functional properties of the pancreas. The disease can destroy the entire body. Destructive changes in the pancreas are a common occurrence among patients with diabetes.
But despite the difficult medical conclusion and the presence of the affiliated processes, it is possible to ensure the necessary functionality of the body. The main thing is to promptly seek qualified help, start treatment, choose a diet and adhere to the prescribed diet.