Treatment and Prevention

Preparation Lizinoton: instructions for use

Lisinoton in pill form is used to normalize blood pressure in the event of a sharp deterioration in the condition, to prevent a hypertensive crisis in chronic hypertension.

International non-proprietary name

Lisinopril - the name of the active substance.

Lisinoton in pill form is used to normalize blood pressure.


C09AA03 - code for anatomic-therapeutic-chemical classification.

Forms of release and composition

Round-shaped tablets are available in blisters of 10 pcs. in each. The structure of 1 tablet includes 5 mg, 10 mg or 20 mg of lisinopril dihydrate.

pharmachologic effect

The drug belongs to antihypertensive drugs (ACE inhibitor).

The medicine has a number of such useful properties:

  1. Reduces pressure in small blood vessels in the lungs.
  2. It improves blood circulation processes, which helps to improve the functioning of the heart.
  3. Positive dynamics of clinical symptoms in hypertension is observed in the first days of drug therapy. And with a sharp cessation of taking the pills, there is no increase in blood pressure, which can be considered pronounced.
The medicine relieves the pressure in the small blood vessels of the lungs.
Positive dynamics of clinical symptoms in hypertension is observed in the first days of drug therapy.
Medical tool improves blood circulation.


You can take the drug, regardless of the meal time, because This factor does not affect the effectiveness and action of Lysinotone.

The maximum concentration of the active substance is observed in the blood plasma 5 hours after taking the medicine.

Lisinopril is absorbed from the rectum into the systemic circulation.

The decomposition products of the active substance in the body are not formed; therefore, the active component is excreted by the kidneys along with urine in unchanged form.

Indications for use

The drug is prescribed for the following diagnoses:

  • increased pressure (in most cases it is used as a means for complex therapy);
  • myocardial dysfunction;
  • acute myocardial infarction (we are talking about the early period).
The drug is prescribed for myocardial dysfunction.
The drug is prescribed at elevated pressure.
The drug is prescribed for acute myocardial infarction.


You can not take the drug in the presence of angioedema in the history of the disease, as well as in the case of individual intolerance to the active substance.

With bilateral stenosis, the use of the remedy is also contraindicated.

How to take Lisinoton

The drug is used for oral administration.

It is important to consider a number of such features:

  1. For hypertension, patients take 0.005 grams per day. In the absence of a therapeutic effect, the initial dose is increased every 3 days by 0.005 g, but not more than 20 mg per day.
  2. If improvement is not observed after 14–20 days, then treatment is supplemented with the use of other antihypertensive medications.
  3. With persistent hypertension requires prolonged therapy with the drug at a dose of 10 mg per day.
  4. In acute myocardial infarction, tablets are taken for 2 months.

The drug is used for oral administration.

With diabetes

The drug does not affect the concentration of glucose in the blood, so taking tablets does not provoke the development of hypoglycemia. But perhaps a high content in the blood of nitrogenous metabolic products excreted by the kidneys (azotemia).

Side effects

The drug causes a lot of undesirable reactions of the body.

Gastrointestinal tract

In rare cases, patients have a stool disorder. Dry mouth and taste changes are common. Hepatitis and jaundice sometimes develop.


There is a decrease in the level of leukocytes and platelets in the blood.

The drug can cause a decrease in the level of white blood cells and platelets in the blood.

central nervous system

Severe headaches and dizziness are possible. Patients note increased fatigue, a constant desire to sleep, a decrease in mood. Men often experience erectile dysfunction and decreased sexual desire.

Since the cardiovascular system

Rarely, patients experience intense pain in the chest, pressure decreases and heartbeat increases.

Sometimes cerebrovascular stroke occurs in people with chronic hypertension.

Musculoskeletal and connective tissue

Often there are muscle cramps and soreness in the back.

On the part of the respiratory system

Frequent cases of dry cough.

After taking the medicine, there are frequent cases of dry cough.

From the genitourinary system

Rarely observed impaired renal function.

By the immune system

Rarely observed swelling of the face, nasal mucosa and larynx.


Perhaps increased sweating and the appearance of an itchy rash on the skin (urticaria).

Influence on ability to operate mechanisms

There are dizziness among the side effects, so there is a high risk of loss of control over driving.

special instructions

It is important to consult a doctor before starting Lizinoton treatment.

Use in old age

There is a slow excretion of the active substance, which leads to a pronounced decrease in blood pressure.

It is important to consult a doctor before starting Lizinoton treatment.

Appointment to children

Up to 18 years of age, taking pills is contraindicated.

Use during pregnancy and lactation

The active substance penetrates the placental barrier, so you can not use the drug in any trimester. For newborns who have been exposed to ACE inhibitors at the stage of intrauterine development, it is recommended to establish observation in order to timely detect severe oliguria (reduce the amount of urine excreted).

During breastfeeding, it is also not recommended to carry out treatment with Lysinotone.

Use in violation of kidney function

In renal failure caused by a narrowing of the lumen of the artery that feeds the kidney, it is necessary to control the concentration of potassium in the blood.

Use in violation of the liver

Adjustment of the initial dose to patients with severe liver dysfunction is required.


In case of exceeding the dose recommended by a doctor, the following symptoms are observed:

  • urinary retention;
  • high level of irritability;
  • constipation.

In case of exceeding the dose recommended by the doctor, urination is delayed.

It is recommended to restore the water-electrolyte balance, and dialysis is used to remove lisinopril from the body.

Interaction with other drugs

It is important to consider the following:

  1. At the same time taking diuretics decreases excretion of potassium.
  2. When Lysinotone and Indomethacin are used together, the effectiveness of lisinopril is reduced.
  3. In the case of simultaneous use of antacids, the absorption of the active component Lysinotone from the GIT is impaired.

Compatibility with alcohol

Ethanol enhances the action of the active substance.


The use of Lysinotone H is recommended. The drug is a combination of lisinopril (10 mg or 20 mg) and hydrochlorothiazide (12.5 mg).

Lisinoton N has a diuretic and hypotensive effect at the same time.

This tool has a diuretic and hypotensive effect at the same time.

Lysinotone vacation conditions from the pharmacy

In most cases, a doctor's prescription is required.

Can I buy without a prescription

In many pharmacies in Russia, the drug is available for sale.

Price for Lisinoton

The cost of the drug varies from 120 to 200 rubles.

Drug storage conditions

It is important to store the product in a dark and cool place.

Shelf life

Use tablets for 3 years from date of manufacture.

The active substance penetrates the placental barrier, so you can not use the drug in any trimester.

Lisinoton Manufacturer

The drug is manufactured in Iceland by the pharmaceutical company Actavis.

Doctors reviews about Lisinoton

Nikolay, 38 years old, Moscow

Treatment with inhibitors allows to achieve a positive result in a short time. But he noted the frequently occurring side effects of the urinary system (urinary retention).

Mikhail, 47 years old, St. Petersburg

I like the therapeutic properties of this drug. The active component supports the work of the heart against the background of chronic hypertension, but requires a long course of treatment.

Preparations for lowering blood pressure

Patient Reviews

Marina, 50, Omsk

The pressure returned to normal after a week of taking the pills, but her friend's condition worsened. No side effects have arisen. Dry mouth was already on the 2nd day of Lysinotone. I recommend initially to consult a doctor.

Elena, 43 years old, Ufa

Faced with vertigo in the first days of taking the funds. The doctor canceled the drug. But I heard that many people take pills to cope with the problem of high blood pressure in chronic heart failure.

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