Treatment and Prevention

How to use the drug Torvakard?

Torvacard is a drug that is part of the group of statins. During the use of the drug has proven effective in treating patients with cardiovascular pathologies, the presence of pathological levels of lipids in the blood. Often appointed as a preventive agent, it helps reduce the risk of death.

ATX

According to the classification of drugs, the tool has the code C10AA05. The active ingredient is atorvastatin.

Torvacard is a drug that is part of the group of statins.

Forms of release and composition

This drug is available in pill form. In shape, they can be oval oblong or round biconvex, covered with a shell.

Packaging - blisters of foil and plastic, each of them contains 10 tablets. Blisters pack in cardboard packs, which contain a different number of tablets (30 or 90 pieces).

The composition includes active substances and additional.

Packaging - blisters of foil and plastic, each of them contains 10 tablets.

In the list of active components:

  • atorvastatin calcium in the amount of 10, 20 mg or 40 mg (these data indicate on the package).

As additional ingredients are present:

  • magnesium stearate;
  • microcrystalline cellulose;
  • low-level hyprolosis;
  • colloidal silicon dioxide;
  • magnesium oxide;
  • lactose monohydrate;
  • croscarmellose sodium.

The film shell is made of a small amount of talc, macrogol 6000, titanium dioxide and hypromellose 2910/5.

pharmachologic effect

The drug is a member of the drug group of statins, HMG inhibitors. These drugs can affect the level of triglycerides, plasma cholesterol, active metabolites.

The drug is a member of the drug group of statins, HMG inhibitors. These drugs can affect the level of triglycerides, plasma cholesterol, active metabolites.

The remedy is carried by the blood through the body and reaches the peripheral tissues. It operates in several directions:

  • level of a cholesterol indicator is reduced by 30-46%;
  • 30-50% can reduce the content of apolipoprotein;
  • 41-61% reduces the content of LDL receptors (low density lipoprotein index);
  • up to 33% can reduce the amount of triglycerides;
  • the rate of blood apolipoprotein A and HDL cholesterol increases.

Conducting numerous tests proved the high efficacy of the drug. It gives a positive trend even in patients for whom therapy with drugs of the group of statins was ineffective.

Pharmacokinetics

Pharmacokinetics has the following features. Each time you take the drug, the HMG-CoA reductase enzyme is blocked for a period of 20 to 30 hours.

Eating together with taking a pill leads to a slowing down of the effect of the active substance, but this factor does not reduce the effectiveness.

Excretion to a greater extent occurs through the intestines. With urine no more than 2% is excreted.

Eating together with taking a pill leads to a slowing down of the effect of the active substance, but this factor does not reduce the effectiveness.

Indications for use

In the form of a therapeutic and prophylactic agent is prescribed in the following cases:

  1. Primary hypercholesterolemia, a combined type of hyperlipidemia. Pathology can be represented by hypercholesterolemia heterozygous familial and non-familial. In these cases, medication is combined with a special diet.
  2. Disbetalipoproteinemia (according to Fredrickson type III) and high serum TG level (according to Fredrickson type IV).
  3. Some diseases of the cardiovascular system. In this case, the drug is prescribed to patients who are at risk for coronary heart disease. It may be people over 55 years old who have had a stroke, have a long smoking history, and are suffering from diabetes. In addition, it may be arterial hypertension or left ventricular hypertrophy.

Contraindications

Instructions for use calls for several diseases and conditions under which prescribing the drug is not recommended:

  • liver disease (which are active type);
  • in case of liver failure (especially those cases that are referred to on the Child-Pugh scale to severity A and B);
  • individual hypersensitivity of the patient to one or more components of the drug;
  • in women, the period of pregnancy and breastfeeding;
  • a number of hereditary diseases associated with intolerance or lactose deficiency;
  • children and adolescents under 18 years of age (the effect of the drug on children has not been studied).
Children under 18 years of age to prescribe medication is not recommended.
During pregnancy and lactation, it is not recommended to prescribe the drug.
In case of liver diseases, it is not recommended to prescribe the drug.

Carefully

The list of contraindications did not include some pathological conditions and diseases in which the active substance can disrupt the functioning of internal organs. With the following diagnoses, the doctor may prescribe a drug to the patient under close supervision:

  • metabolic or endocrine disorders;
  • the presence of alcoholism in a patient;
  • uncontrolled epilepsy;
  • impaired water-electrolyte balance, characterized by clear manifestations;
  • history of liver pathology (transaminases);
  • arterial hypotension;
  • diabetes;
  • acute severe infections (sepsis is one of the typical examples);
  • the presence of rhabdomyolysis.

If the patient has alcoholism, the doctor may prescribe the drug under close supervision.

How to take torvacard

Treatment and prevention with the use of tablets should be carried out in conjunction with lipid-lowering drugs (therapeutic diet). This factor has a great influence on the outcome of therapy.

The dose of the drug for each patient is calculated individually, depending on the diagnosis and administration of other medications.

Often the amount of medication is advised to gradually increase. So, at the very beginning of treatment, the daily dose can reach 10 mg and gradually increase to 80 mg.

Daily dosage prescribed by a doctor, take 1 time. There are no special requirements for eating. Tablets can be taken on an empty stomach, before, after or during meals. The last option is most preferred.

For the timely correction of therapy while taking medication from the group of statins, the patient should be tested regularly. Efficiency begins to manifest itself in 10-14 days, and the maximum rate is possible at 4 weeks from the start of use.

With diabetes

Atorvastatin is able to increase blood glucose levels, which increases the risk of developing diabetes. In patients who have already made such a diagnosis, it increases the level of glucose slightly.

Atorvastatin is able to increase blood glucose levels, which increases the risk of developing diabetes.

At the same time, the prevention of cardiovascular diseases (arterial hypertension, IHD) in people prone to their development is more important than some side effects. An important rule in the treatment of statins is to comply with the dosage and regular testing.

Side effects

Side effects while taking the drug are rare. Most patients tolerate treatment well.

However, the manufacturer warns about the possible manifestation of the reaction of the organism. The presence of a particular sign requires the abolition of the medication and treatment to a doctor.

Gastrointestinal tract

The digestive system can respond to changes in stool patterns (diarrhea or constipation), dyspepsia, and nausea. In rare cases, there is pain in the abdomen, bouts of vomiting and the appearance of pancreatitis.

In rare cases, abdominal pain, bouts of vomiting and the appearance of pancreatitis may occur after taking the drug.

Hematopoiesis

In some patients, plasma atorvastatin levels may lead to lymphadenopathy, thrombocytopenia, or anemia.

central nervous system

The list of side effects of this type can include:

  • various sleep disorders are sleepiness, insomnia, and the appearance of nightmares;
  • headaches;
  • in some cases, paresthesia (tingling sensations in the arms, legs, or other parts of the body);
  • convulsions;
  • increased mental irritability (referred to as hyperesthesia);
  • frequent dizziness;
  • bouts of depression.

From the side of the central nervous system, headaches can occur, dizziness.

On the part of the urinary system

In some cases, the appearance of nephritis, cystitis, urinary incontinence. Men have the risk of developing impotence or problems with ejaculation. Women were diagnosed with vaginal bleeding.

On the part of the respiratory system

Doctors note the possible occurrence of pain, concentrated in the region of the trachea and pharynx, nosebleeds, lung disease.

By the immune system

The most frequent response to taking pills is an allergic reaction, which is expressed by itching, rashes, slight swelling.

The most frequent response to taking pills is an allergic reaction, which is expressed by itching, rashes, slight swelling.

Metabolism

Among these side effects are hypoglycemia or hyperglycemia, a sharp loss of body weight (anorexia) or, on the contrary, weight gain.

On the part of the organ of vision

There are several reaction options - a decrease in clarity of vision, a feeling of dry eyes, in some cases, hemorrhages in the eye are possible.

Liver and biliary tract

There is a small risk of developing pathologies such as cholestasis, liver failure, and hepatitis.

special instructions

Prescribing the remedy to restore normal cholesterol should only be after applying a therapeutic diet, increasing physical activity, reducing body weight (for people suffering from obesity).

Biochemical parameters of hepatic function require regular monitoring. Their level is checked at 6 and 12 weeks after the start of treatment. Additional checks are needed after increasing the dosage of the drug.

Compatibility with alcohol

Taking a statin, it is desirable to abandon the use of alcohol-containing beverages. This can cause side effects.

Taking a statin, it is desirable to abandon the use of alcohol-containing beverages. This can cause side effects.

Influence on ability to operate mechanisms

The instruction does not contain any mention of the need to cease the control of the mechanisms and the vehicle.

Use during pregnancy and lactation

Women both during pregnancy and during breastfeeding drug is prohibited to receive. This is due to the negative effect of the active substance on the health and life of the fetus. It is also not recommended to prescribe this medicine to women of reproductive age who use ineffective methods of contraception.

Appointment of Torvacard children

Children and adolescents up to 18 years of age, this medication is not prescribed. Information about the effect of the active substance on the child's body is not available.

Use in old age

Prescribing medication is based on a patient’s diagnosis or a history of the disease. Before starting a course of therapy and during the course of treatment, the physician must monitor the patient’s condition.

Prescription medication for elderly patients is based on a diagnosis or a history of the disease.

Overdose

Overdose is manifested by those symptoms that are present as side effects. There is no specific antidote for this active substance. Symptomatic therapy is carried out to restore normal well-being.

Interaction with other drugs

Atorvastanin with simultaneous use can change its effect and affect the activity of other drugs.

  1. With immunosuppressive and antifungal agents. The active substance becomes less active (a reduced amount of the element is present in the blood).
  2. With aluminum and sodium hydroxide. Concentration is often reduced by a third.
  3. With spironolactone, cimetidine and ketoconazole, endogenous steroid hormones are often reduced.
  4. With the use of Colestipol, the level of the active ingredient is reduced by a quarter.
  5. With oral contraceptives. Interacts only with those that contain norethindrone or ethinyl estradiol. The level of concentration of norethindrone and ethinyl estradiol in the blood increases.

Manufacturer

The release of the drug and the primary packaging is carried out by the company Zentiva, it is located in the Slovak Republic.

The release of the drug and the primary packaging is carried out by the company Zentiva, it is located in the Slovak Republic.

Secondary packaging is carried out by both Zentiva and the Russian company Zio Health JSC (in Moscow).

Analogs

The active substance is atorvastatin, therefore, the same effect will have those drugs that contain this component. In addition, there are a number of medicines that have a different composition, but similar actions.

Drugs analogues:

  • Lipona;
  • Vasator;
  • Atomax;
  • Rosuvastatin;
  • Tulip;
  • Atoris;
  • Liprimar.

Tulip is an analogue of Torvakard.

Pharmacy vacation terms

Buying a drug requires a prescription.

Can I buy without a prescription

According to the instructions, the medicine is not released without a prescription.

Price for torvakard

The cost of the drug depends on several features: the number of pills in one pack, the price policy of pharmacies.

Drug storage conditions

This medicine does not need special storage conditions.

The shelf life of the drug Torvakard

Under proper storage conditions, the medicine is stored for 4 years.

Torvakard: analogues, reviews, instructions for use
How to take medicine. Statins

Reviews of torvakard

Over the years of its existence on the pharmacology market, the tool has proven to be highly effective. This is evidenced by the reviews of doctors and patients.

Cardiologists

Konstantin, cardiologist, medical practice experience 14 years

For patients with coronary artery disease (coronary heart disease), this drug gives high efficiency. However, this can be achieved only with the use of a therapeutic diet. Of the benefits worth mentioning a small number of side effects and ease of use.

For patients with coronary artery disease (coronary heart disease), this drug gives high efficiency. However, this can be achieved only with the use of a therapeutic diet.

Of patients

Irina, 45, Ufa

With the diagnosis of diabetes mellitus, in addition to other drugs, this medicine was prescribed. Accept a couple of months. Despite the large number of these side effects, there were no discomfort. The only thing - you need to often pass tests for control.

Watch the video: Statins should NOT have been approved for use; Peter Langsjoen MD (September 2019).