Treatment and Prevention

How to use the drug Vazotenz?

Vasotensom therapy is often prescribed to people suffering from arterial hypertension. Due to the combined action of this drug not only contributes to the normalization of blood pressure, but also increases the body's endurance during exercise and reduces the risk of progression of a number of diseases of the cardiovascular system. This tool should be applied as prescribed by a doctor in a dose not exceeding that specified in the instructions attached to the medication.

International non-proprietary name

INN Medicinal Product - Losartan.

Vasotensom therapy is often prescribed to people suffering from arterial hypertension.

ATH

In the international classification of ATC, this medicine has the code C09CA01.

Forms of release and composition

The main active ingredient of Vazotenza is losartan potassium. Additional components of the drug include croscarmellose sodium, mannitol, hypromellose, magnesium stearate, talc, propylene glycol, etc. In addition to losartan, Hydrochlorothiazide is included in the composition of Vazoten.

Vazotenz is available in the form of tablets with a dosage of 25, 50 and 100 mg. Tablets are different rounded shape. They are white coated and, depending on the dosage, have the designation "2L", "3L" or "4L". They are packaged in blisters of 7 and 10 pcs. In a cardboard box there are 1, 2, 3 or 4 blisters and an instruction sheet with information about the preparation.

Vazotenz is available in the form of tablets with a dosage of 25, 50 and 100 mg.

pharmachologic effect

The pharmacological properties of the drug are due to the pronounced hypotensive activity of Vasotenza, the main active component of which is an angiotensin type 2 receptor antagonist. During therapy with vasotens, the active substance of the drug contributes to the reduction of OPSS. The drug lowers the concentration of aldosterone and adrenaline in the blood plasma. This drug has a combined effect, contributing to the normalization of pressure in the small and large circle of blood circulation.

In addition, the active components of the drug reduce the load on the cardiovascular system and have a pronounced diuretic effect. Due to the complex action, treatment with vasotensum reduces the risk of myocardial hypertrophy. This medicine helps to increase the tolerance to physical exertion of patients with pronounced signs of heart failure.

The drug does not inhibit the synthesis of kinase type 2. This enzyme has a destructive effect on bradykinin. When you take this medication, a decrease in blood pressure is observed after 6 hours. In the future, the activity of the active substance of the drug is gradually reduced over 24 hours. With systematic use, the maximum effect is observed after 3-6 weeks. Thus, the drug requires long-term systematic use.

Pharmacokinetics

The active substance Vazotenza is rapidly absorbed into the walls of the gastrointestinal tract. In this case, the bioavailability of funds reaches about 35%. The maximum concentration of the active component in the blood is reached after about 1 hour. Metabolism of the drug occurs in the liver. Subsequently, about 40% of the dose is excreted in the urine and about 60% in the feces.

Indications for use

The use of vasotenza is indicated in the treatment of malignant hypertension. This tool is used in the prevention of hypertensive crises and myocardial hypertrophy. In addition, the drug is often prescribed for the treatment of heart failure. In case of similar pathologies of the cardiovascular system, the drug is used as part of a combination therapy. In addition, the use of Vazotenza is justified in the treatment of patients with individual intolerance to ACE inhibitors.

The use of vasotenza is indicated in the treatment of malignant hypertension.

Contraindications

This medicine cannot be used if the patient has an individual intolerance of its individual components. Treatment with Vasotensum is not recommended if the patient has a tendency to a pronounced decrease in blood pressure. This drug can not be used in the presence of hyperkalemia, as this may aggravate the patient's condition. In addition, the drug can not be used in the presence of signs of dehydration.

Carefully

If the patient has signs of an abnormality in the liver and kidney, treatment with Vasotenz requires special attention from the doctor. In addition, the use of azotens in the treatment of people suffering from Schönlein Henoch disease requires special care. In this case, regular dose adjustment of the drug is required to reduce the risk of severe complications.

How to take vazotenz?

This medication is intended for oral administration. To achieve a therapeutic effect, the prescribed dose to the patient should be taken at 1 time in the morning. Food intake does not affect the absorption of the drug. To stabilize blood pressure and maintain it at a normal level, patients receive a dose of Vazotenza at a dose of 50 mg per day. If necessary, the dose may be increased to 100 mg per day.

If the patient has signs of heart failure, a gradual increase in the dose of Vazotenza is recommended. First, the patient is prescribed medication at a dose of 12.5 mg per day. About a week later, the dose is increased to 25 mg. After another 7 days of taking the remedy, his dose is increased to 50 mg per day.

If the patient has signs of abnormal liver function, treatment with Vasotenz requires special attention from the doctor.

With diabetes

The tool can be used for the treatment of patients with diabetes mellitus type 2, with no signs of the development of complications of the disease. In this disease, the drug is most often prescribed at a dose of 50 mg per day.

Side Effects of Vazotenza

The active component of azotens is well tolerated, therefore the development of side effects is extremely rare.

Gastrointestinal tract

When treating with a vase pump, a patient may experience nausea and abdominal pain. Stool disorders, dry mouth, flatulence, anorexia rarely occur as a result of taking Vazotenza.

From the musculoskeletal system

Arthralgia and myalgia may occur during treatment with Vasotenz. Rarely, patients experience pain in the legs, chest, shoulders and knees.

Features of the treatment of hypertension drug Lozap
Quickly about medications. Losartan

central nervous system

Approximately 1% of patients undergoing Vasotensom therapy have symptoms of asthenia, headaches and dizzy spells. Sleep disturbances, morning drowsiness, emotional lability, signs of ataxia, and peripheral neuropathy may in rare cases appear when treated with Vasotensum. Perhaps a violation of taste and visual impairment. In addition, there is a risk of impaired limb sensitivity.

On the part of the respiratory system

Adverse effects from the respiratory system are extremely rare. Coughing and nasal congestion are possible. The use of Vazotenza can create conditions for the development of diseases of the upper respiratory tract. Rhinitis, bronchitis and disapnea are rarely observed with this drug.

On the part of the skin

May cause excessive sweating or dry skin. In rare cases, the development of erythema and increased sensitivity to light. Alopecia is possible with the use of vasotens.

From the genitourinary system

Acceptance of vasotenza can create conditions for the development of infectious diseases of the urinary tract. In rare cases, patients complain of frequent urination and renal dysfunction. In men with Vasotenzom therapy, a decrease in libido and the development of impotence can be observed.

Perhaps the appearance of dry skin.

Since the cardiovascular system

With prolonged therapy with vasotensom, a patient may develop orthostatic hypotension. Possible attacks of stenocardia and tachycardia. In rare cases, taking the drug becomes the cause of anemia.

Allergies

The most common use of Vasotenta causes mild allergic reactions, expressed by itching, urticaria, or skin rash. Rarely observed the development of angioedema.

Influence on ability to operate mechanisms

The drug can cause drowsiness and a decrease in concentration, therefore, when treating with Avazotenz, care must be taken when controlling complex mechanisms.

special instructions

Before initiating therapy with Vasotenz, it is necessary to correct dehydration.

Use during pregnancy and lactation

The efficacy and safety of using azotens during pregnancy has not been fully studied. At the same time there is evidence of the negative effect of the active substance of the drug on the fetus in the 2nd and 3rd trimester of pregnancy. This increases the risk of the child developing severe malformations and fetal death. If necessary, treatment may be recommended refusal to breastfeed.

With prolonged therapy with vasotensom, a patient may develop orthostatic hypotension.

Purpose of Vazotenz to children

This medication is not prescribed to children and adolescents under 18 years of age.

Use in old age

When treating the elderly, it is necessary to control the level of potassium in the blood. You must start taking the medication with the minimum therapeutically effective dose.

Use in violation of kidney function

The tool can be used in the treatment of patients with impaired renal function, but in this case it is possible to increase the level of uric acid in the blood. In addition, control of the level of potassium in the blood of these patients is required.

Use in violation of the liver

In case of pathologies with impaired liver function, incl. cirrhosis, patients are prescribed a reduced dose of azotensis, since diseases of this organ cause an increase in the concentration of the active ingredient of the drug in the blood.

Overdose of Vazotenza

When exceeding the recommended dosage of the drug in patients may experience severe tachycardia. Perhaps a strong decrease in blood pressure. When signs of overdose appear, symptomatic treatment and forced diuresis are prescribed, since hemodialysis is ineffective in this case.

This medication is not prescribed to children and adolescents under 18 years of age.

Interaction with other drugs

It is allowed to use Vazotenza in combination with other antihypertensive drugs. In patients treated with diuretics, a critical reduction in blood pressure is possible. Acceptance of Vazotenza enhances the effect of sympatholytics and beta-blockers. When combined with the use of potassium supplements with potassium preparations, the risk of hyperkalemia increases.

Compatibility with alcohol

When treating with Avazotenz, it is not recommended to take alcoholic beverages.

Analogs

For drugs that have a similar therapeutic effect include:

  1. Lozap.
  2. Cozaar.
  3. Gifted
  4. Losokor.
  5. Lorista.
  6. Zisacar
  7. Bloktran.
  8. Lozarel etc.

Pharmacy vacation terms

The drug is commercially available.

Can I buy without a prescription

This medication can be purchased without a prescription.

Price for vazotenz

The cost of the drug in pharmacies ranges from 115 to 300 rubles, depending on the dosage.

One of the most famous analogues of the drug is Lozap.
Cozaar is an analogue of the drug Vazotenz.
Similar drug is Presartan.
Analogue of the drug Vasotens is Lorista.
Lozarel is one of the well-known analogues of the drug Vasotens.

Drug storage conditions

The product should be stored in a dark place at temperatures up to + 30 ° C.

Shelf life

You can use the drug for 3 years from the date of issue.

Manufacturer

The drug is manufactured by AKTAVIS JSC.

Reviews of Vasotens

This drug is often used, so it has a lot of feedback from both doctors and patients.

Cardiologists

Gregory, 38 years old, Moscow

In my medical practice, I often prescribe the use of Vasotenes for patients suffering from arterial hypertension. Due to the combined hypotensive and diuretic effect, the drug not only contributes to the normalization of blood pressure, but also increases the patient's tolerance to physical exertion and reduces the severity of edema. The drug is well tolerated even by older patients. In addition, it is suitable for inclusion in the complex therapy with the use of additional antihypertensive drugs.

Irina, 42, Rostov-on-Don.

I have been working as a cardiologist for more than 15 years and for patients who come with complaints of high blood pressure, often prescribe Vazotenz. The effect of this medication in most cases is sufficient to maintain normal pressure without the need to additionally use diuretics. This drug is well tolerated by patients and rarely causes side effects. Thanks to this, you can effectively use it with long courses.

Igor, 45, Orenburg

I often recommend the use of Vazotenza for patients suffering from heart failure. The drug allows you to gently achieve normalization of blood pressure and reduce the severity of lower extremity edema. The tool is well combined with other drugs used in the treatment of this pathological condition. During his many years of practice, he has never encountered the appearance of side effects in patients using Vazotenz.

When using the medication should be managed with caution complex mechanisms.

Of patients

Margarita, 48 years old, Kamensk-Shakhtinsky

The problem of high blood pressure has been familiar for more than 15 years. At first, the doctors recommended losing weight, walking regularly in the open air and eating right, but the problem gradually worsened. When the pressure began to stand steadily at 170/110, the doctors began to prescribe medicines. Last 3 years I have been treated with Vazotenz. The tool gives a good effect. I accept it in the morning. The pressure has stabilized. Disappeared swelling of the legs. Began to feel more cheerful. Even climbing stairs are now without breathlessness.

Andrey, 52 years old, Chelyabinsk

From the pressure took different drugs. For about a year, a cardiologist prescribed the use of Vazotenza. The tool gives a good effect. To take it you need only 1 time per day. The pressure returned to normal in just 2 weeks. Now I take this medication every day. No side effects are not observed.