Treatment and Prevention

How to use the drug Lantus SoloStar?

Insulin glargine is a hypoglycemic agent, an analogue of human insulin produced by the pancreas. It is obtained by recombining DNA bacteria of the species Escherichia coli.

International non-proprietary name

The international non-proprietary name of the drug is insulin glargine.

Available in the form of syringe pens containing a cartridge of 100 IU / ml 3 ml each (300 U).

Ath

ATH code - A10AE04.

Forms of release and composition

Pills

Insulin Lantus pill form is not available.

Drops

In the form of drops is not available.

Powder

Insulin in powder form is not available.

Solution

The solution for subcutaneous administration is the only form of release of this drug. Available in the form of syringe pens containing a cartridge of 100 IU / ml 3 ml each (300 U). The cartridges are crimped with an aluminum cap on one side and a bromobutyl plunger on the other. One carton contains 5 syringe pens. 1 ml of solution contains 100 PIECES of insulin glargine.

Capsules

Insulin Lantus SoloStar capsule form is not available.

Ointment

Insulin in the form of ointments is not available.

The only indication for the use of insulin syringe pens Lantus SoloStar is diabetes mellitus type one.

pharmachologic effect

The drug insulin glargine has a hypoglycemic effect, that is, reduces blood sugar levels. The decrease in glucose level occurs due to the binding of the insulin given to its receptors, thus affecting glucose metabolism. As a result of this action, by increasing the utilization of glucose in peripheral tissues, its level in the blood decreases.

Pharmacokinetics

The effect of insulin is due to the systemic exposure of the metabolite M1. Insulin and the M2 metabolite were not found in the majority of the studied patients with diabetes mellitus in the circulatory system. But in rare cases, when the metabolite M2 and insulin were detected in the blood, the concentration of both did not depend on the insulin administered glargine.

Indications for use

The only indication for the use of insulin syringe pens Lantus SoloStar is diabetes mellitus type one.

Contraindications

  1. Individual intolerance to insulin glargine and auxiliary substances.
  2. Children under the age of 2 years (due to the lack of clinical studies).
  3. Take with caution during pregnancy.

How to take Lantus SoloStar

Insulin is injected subcutaneously once a day, at the same time. Since it is a long-acting insulin, administration in the evening is most often prescribed, mostly after the last meal. The concentration of sugar in the blood, the dose and time of administration of Lantus SoloStar is determined individually for each patient.

Insulin is injected subcutaneously once a day, at the same time.
The drug is not recommended to be taken during pregnancy.
The drug is contraindicated in children under 2 years.

With changes in weight, lifestyle and other circumstances relating to the state of the body, it is necessary to adjust the daily dosage. But any changes in time and dosage should be carried out strictly under the supervision of an endocrinologist.

How to use a pen

The injection site should not be the same; the injection site should be changed. The recommended area for insulin injection is the subcutaneous fatty tissue of the shoulders, hips, or abdomen. Used syringe pens should be disposed of. Their reuse is prohibited. To avoid infection, one syringe pen should be used by one patient.

Before using the syringe for safety reasons, it is necessary to carefully read the instructions and verify the integrity of the package and the cartridge with the solution, and also check the label for compliance. Lantus SoloStar in the form of a syringe pen should be gray with a button for the injection of purple color. The solution should not contain any extraneous inclusions. The liquid should be clear as water.

After inspecting the syringe, insert the needle. You can only use special needles that are compatible with this pen. The needles change with each subcutaneous injection.

Immediately before the introduction of the needle should ensure that there are no air bubbles in the solution. To do this, measure 2 ml of the solution, remove the needle caps and set the syringe in a vertical position with the needle up. Wait until all the air bubbles are at the top, tapping the handle. Only after that press all the way to the button for insertion.

As soon as the insulin appears on the needle tip, this will mean that the needle is installed correctly, and you can proceed to the injection.

The minimum dose in the pen is 1 IU, the maximum can be set to 80 IU. if necessary, the introduction of a dose exceeding 80 U, should be 2 injections. After completion, a “0” should be displayed in the dosing window, and only after that a new dose can be set.

When administering insulin subcutaneously, the patient should be aware of the rules for conducting such injections by the attending physician.

Insulin treatment Lantus SoloStar is prescribed by the attending physician, self-prescribing insulin injections is unacceptable.

After administering insulin, the needle must be disposed of. Repeated use is not allowed. After removing the needle and completing the procedure, you must close the cap of the syringe handle.

Diabetes Treatment

Insulin treatment Lantus SoloStar is prescribed by the attending physician, self-prescribing insulin injections is unacceptable. In patients with diabetes mellitus monitoring of blood sugar is mandatory. This will help to choose the right dosage and time for the introduction of insulin.

Side Effects of Lantus Solostara

Metabolism

Most often, the side effect is manifested in the form of hypoglycemia. It occurs when the required dose of the administered drug is exceeded.

Symptoms of hypoglycemia will be: a sudden feeling of tiredness, weakness of the body, dizziness and nausea.

The immune system

In rare cases, allergic reactions such as skin rashes, angioedema, bronchospasms, or lowering blood pressure may occur.

central nervous system

Rare cases of violations or distortion of taste, that is, dysgeusia.

From the musculoskeletal system and connective tissue

Adverse reactions in the form of myalgia are rare.

Adverse reactions in the form of myalgia are rare.

By the organs of vision

Retinopathy, rarely - visual impairment.

On the part of the skin

Often there is a reaction in the form of lipodystrophy, the pathology of adipose tissue.

Allergies

Redness, pain, itching, burning, allergic reactions in the form of urticaria, edema or inflammation are possible at the injection sites.

Influence on ability to operate mechanisms

Does not affect the ability to control machinery and vehicle, subject to the prescribed dosages.

special instructions

Use during pregnancy and lactation

The use of insulin glargine for women during pregnancy is possible if there are clinical indications.

The use of insulin during lactation is possible only after consulting a doctor, who adjusts the dosing regimen and time.

The use of insulin during lactation is possible only after consulting a doctor, who adjusts the dosing regimen and time.

Appointment of Lantus SoloStar to children

Lantus SoloStar shows teens and children from the age of two.

Use in old age

Elderly patients are advised to use a moderate initial dose, gradually increasing it.

Use in violation of kidney function

The need of the drug in patients with impaired renal functioning may be reduced due to its slow elimination. Elderly patients with renal failure have a persistent decrease in the need for injections of the drug.

The need of the drug in patients with impaired renal functioning may be reduced due to its slow elimination.

Use in violation of the liver

In patients with severe hepatic impairment, the need for managing the drug is also reduced.

Overdose of Lantus Solostara

Overdose can lead to severe forms of hypoglycemia, the development of neuroglycopenia, which can threaten the patient's life. At the first signs of a sharp decline in blood sugar, the patient feels a sudden general weakness of the body, impaired concentration, drowsiness and dizziness. Treatment consists of ingesting fast-absorbing carbohydrates. For more severe forms, intramuscular or subcutaneous injection of glucose solution will be required.

Interaction with other drugs

There should be no other drugs in the solution cartridge. Such a mixture of drugs can affect the duration of the insulin injected, which will adversely affect the patient's condition.

Simultaneous use with oral hypoglycemic drugs can enhance the action of insulin glargine. Diuretic drugs, phenothiazine derivatives, somatotropin, estrogen and gestagen hormones, on the contrary, weaken the hypoglycemic effect of the drug.

Compatibility with alcohol

Taking alcohol can both increase and decrease the hypoglycemic effect of the drug.

Taking alcohol can both increase and decrease the hypoglycemic effect of the drug.

Analogs

Among the analogues of the drug, doctors distinguish Tujeo SoloStar.

Pharmacy vacation terms

Released strictly by prescription.

Can I buy without a prescription

To purchase the drug Lantus, you must provide a prescription sheet with a print clinic.

How much is Lantus SoloStar

The price of the drug varies from 2900 rubles. up to 3400 rubles per pack.

Drug storage conditions

The drug is stored at a temperature not lower than + 2 ° C and not higher than + 8 ° C, it can not be frozen. Store the started pen at room temperature out of the reach of children.

Lantus SoloStar Syringe Pen
What you need to know about insulin Lantus

Shelf life

Closed packages are stored for 3 years from the date of issue. The opened syringe pens - 4 weeks.

Manufacturer

  1. Germany, Sanofi-Aventis Deutschland GmbH. Industrialpark Hoechst, D-65926, Frankfurt am Main.
  2. Sanofi-Aventis, France.

Lantus SoloStar Reviews

Svetlana S., 46 years old, Nizhny Novgorod: “When a loved one was diagnosed with type I diabetes, they didn’t know what to do, how to treat it, and whether diabetes was treated. The attending physician explained that it was necessary to visit an endocrinologist once a month write prescriptions for concessionary drugs. It was insulin glargine and isophane. One of the drugs turned out to be Lantus Solostar, the doctor clearly determined the time of administration and dosage. The prick began in the fatty layer on the abdomen in the evening shortly before bedtime. still "long."

Six months later, at one of the receptions, the doctor said that Lantus was not in pharmacies now, and prescribed another drug of the same effect. Since we are familiar with this disease not so long ago, we could not even think how much another drug could affect. While they were pricking Lantus, they did not notice any problems with the level of sugar, they always strictly measured its level in the blood, followed a diet and maintained physical activity. The condition was satisfactory.

But for several days we have been introducing another drug, and something incomprehensible has been going on with glucose levels. If Lantus sugar was 5-7, now it is 12-15. We will buy Lantus at our own expense, until it appears in the preferential pharmacies. "

Kirill K., 32, Ust-Katav: “I tried several insulin analogs of Lantus, among them Tujeo SoloStar. I cannot say by efficiency that one is better and the other is worse. When applying this or that insulin, dosage adjustment is necessary. If correctly calculated time of administration and dosing regimen, problems with hypoglycemia can be avoided. It is important to maintain a diet, at the same time not be limited to proteins only and follow the exercise regime. "

Watch the video: How to Use an Insulin Pen - Mayo Clinic Patient Education (September 2019).